# The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation

Van Dongen HP, Maislin G, Mullington JM, Dinges DF · Sleep 26(2):117–126 · 2003



## Key finding

Two weeks at 6 h/night produced deficits equal to two nights of total deprivation — while subjects felt only mildly sleepy. You adapt to feeling tired, not to being impaired.



[Read the paper](https://pubmed.ncbi.nlm.nih.gov/?term=The+cumulative+cost+of+additional+wakefulness:+dose-response+effects+on+neurobehavioral+functions+and+sleep+physiology+from+chronic+sleep+restriction+and+total+sleep+deprivation)

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