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Impact of sleep debt on metabolic and endocrine function
Spiegel K, Leproult R, Van Cauter E · Lancet 354(9188):1435–1439 · 1999
Key finding
Six nights of 4 h sleep impaired glucose tolerance and raised evening cortisol in healthy young men.
Citation
Related studies
Insufficient sleep undermines dietary efforts to reduce adipositySame calorie deficit, 5.5 h vs 8.5 h sleep: the short sleepers lost 55% less fat and 60% more lean mass, and were hungrier.Effect of sleep extension on objectively assessed energy intake among adults…Extending sleep by ~1.2 h cut energy intake by ~270 kcal/day with no diet advice — participants simply ate less.Brief communicationTwo nights of 4 h sleep raised ghrelin, lowered leptin and increased appetite ~24%, especially for calorie-dense carbs.Effects of experimental sleep restriction on weight gain, caloric intake, and…Sleep-restricted adults gained ~1 kg in 5 days, mostly from late-night eating.Meta-analysis of short sleep duration and obesity in children and adultsShort sleep associated with ~55% higher odds of obesity in adults across 30 studies.
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