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The effect of sleep restriction, with or without high-intensity interval exercise, on myofibrillar protein synthesis in healthy young men
Saner NJ, Lee MJ, Pitchford NW, et al. · Journal of Physiology 598(8):1523–1536 · 2020
Key finding
Five nights of 4 h sleep reduced muscle protein synthesis ~18%; HIIT during restriction preserved it.
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Insufficient sleep undermines dietary efforts to reduce adipositySame calorie deficit, 5.5 h vs 8.5 h sleep: the short sleepers lost 55% less fat and 60% more lean mass, and were hungrier.Effect of sleep extension on objectively assessed energy intake among adults…Extending sleep by ~1.2 h cut energy intake by ~270 kcal/day with no diet advice — participants simply ate less.Brief communicationTwo nights of 4 h sleep raised ghrelin, lowered leptin and increased appetite ~24%, especially for calorie-dense carbs.Impact of sleep debt on metabolic and endocrine functionSix nights of 4 h sleep impaired glucose tolerance and raised evening cortisol in healthy young men.Effects of experimental sleep restriction on weight gain, caloric intake, and…Sleep-restricted adults gained ~1 kg in 5 days, mostly from late-night eating.
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